Alterações motoras, extensão da lesão e gravidade da epilepsia no espectro ulegiria/cistos porencefálicos

Abstract

Introduction: Lesions hypoxic-ischemic pathologies can cause a higher or lesser degree, depending on when they occur. In postnatal insults, is the common occurrence of scarring, characterizing ulegyria and/or cysts porencephalic (U/PC).Objectives: To associate the location, extent and severity of brain injury in the spectrum U/PC, with characteristics of epilepsy, motor abnormalities and their impact on activities of daily living (ADLs).Methods: We evaluated 21 patients (15 men and 6 women, aged between 15 and 39 years, mean 25.66 SD 7.12) with epilepsy and brain injury by U/PC attending the epilepsy clinic of the Neurology Service São Lucas Hospital of the Catholic University of RS. All patients underwent MRI, EEG, motor and functional assessment.Results: Fifteen patients (71%) presented U, 2 (9.8%) PC and 4 (19.2%) U + PC. All EEGs were abnormal, with a predominance of slowing multilobar (66.6%) and multilobar discharges (71%). The vast number of patients (47.6%) had a combination of simple partial seizures (SPS), complex (CPS), evolving to secondarily generalized (GTS). Decreased balance and difficulty in performing activities of daily living were common to 21 patients.Conclusion: motor abnormalities resulting from brain damage, coupled with the occurrence of seizures impact the functional capacity of patients with U/PC