Alterações de sintomatologia psiquiátrica em pacientes obesos submetidos ao Bypass Gástrico

Abstract

Background: Several studies indicate increases of psychiatric symptoms in obese patients however there is no consensus on evolution of these symptoms after bariatric surgery. Objective: Our study analyzed changes in psychiatric symptoms in obese patients at Center Obesity and Metabolic Syndrome (COMPUCRS) after surgery treatment. Methods: This cohort prospectively followed obese patients who underwent bariatric treatment. We applied standard psychiatric scales: Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Binge Eating Scale (BES) and Symptom Check List- 90-R in baseline, 6-months and 1-year after Roux-en-Y gastric bypass (RYGB). Changes in scores are evaluated and associated with clinical and socio demographic status. Results: In our cohort, 289 patients are white (93.1%), 75.8% are woman with 37.65 ± 10.31 years old, entered to National Health System-SUS (57.4%) and 56.7% make use psychiatric medications. The mean body mass index (BMI) was 46.8 ± 7.6; 33.9 ± 6.2 and 29.9 ± 5.4 kg/m2 in baseline, 6-months and 1-year respectively (p<0.001). After surgery, all psychiatric symptoms showed a significant decline in scores of standard scales during follow-up. Beck Depression Inventory: 8.9 (7.8 to 0.1) vs 3.2 (2.7 to 3.7) and 2.4 (1.9 to 2.9); Beck Anxiety Inventory: 5.9 (5.1 to 6.8) vs 2.2 (1.8 to 2.6) and 1.8 (1.5 to 2.3); Binge Eaten Scale: 6.7 (5.8 to 8.0) vs 2.0 (1.6 to 2.5) and 1.4 (1.1 to 1.9) (p<0.001). All subscales of Symptom Check List 90-R showed a significant decline following 1-year after bariatric surgery (p<0.001). Conclusion: In one year, a significant reduction was observed in all scores of the assessment of psychiatric symptoms and substantial weight loss in obese patients after RYGB.