O uso da ressonância magnética de corpo inteiro com contraste endovenoso no mieloma múltiplo

Abstract

Introduction-objective: Retrospective study to compare the accuracy of nuclear magnetic resonance with and without intravenous contrast in multiple myeloma. Methods: Thesis developed in collaboration with the Irmandade da Santa Casa de Misericórdia de Porto Alegre (ISCMPA), [CAAE: 83269817.1.0000.5335; Process Number: 2,974,279]. Data collection was performed among the entire population diagnosed from April 2017 to November 2018, ISCMPA, RS - Brazil. This project has financial support from the Foundation for Research Support of the State of Rio Grande do Sul, Protocol 02/2017 - PqG, Process Number: 17 / 2551-00001 007-8. Results: Fifty-four patients with newly diagnosed multiple myeloma were prospectively submitted to MRI of the entire body. In all patients included, a bone marrow biopsy was performed on the iliac crest. The images were evaluated by two specialist radiologists (10 years of experience in MRI) in a consensual reading. The skeleton was divided into 6 regions. We did not identify differences between the accuracy of the method with and without contrast, 92.5 (82.1 to 97.4) and 94.4 (84.6 to 98.8), respectively. The values of sensitivity, specificity, positive predictive value (PPV) and negative (NPV) values were also similar. Conclusion: The accuracy of the whole body resonance method did not show differences between its use with and without contrast, as well as the values of sensitivity, specificity, PPV and NPV.