Avaliação dos níveis séricos de paratormônio e vitamina D em homens com lesão medular por traumatismo

Abstract

Individuals with spine cord injury are more vulnerable to bone loss due to reduced physical activity and lower sun exposure, which may reflect the values of parathyroid hormone (PTH) and vitamin D. Objective : Measure serum PTH, calcium and vitamin D in patients with spinal cord injury by trauma. Methods : Cross-sectional study in men with spinal cord injury of the Associação dos Lesados Medulares do Rio Grande do Sul (LEME) and Associação Canoense de Deficientes Físicos (ACADEF), Brazil. It was applied a questionnaire with socioeconomic and health data, and the measurement of PTH, calcium and vitamin D. For data analysis we used the linear correlation and chi-square. Were significant p values ≤ 0.05. Results : The mean age of participants was 35.52 ± 9.78 years. The mean time lesion was 6.09 ± 5.55 years (6.07 ± 5.87 for paraplegia and 6.17 ± 4.55 years for tetraplegia). The mean concentration for vitamin D was 19.04 ± 6.98 ng / mL (20.13 ± 7.18 for paraplegia ng / mL and 15.27 ± 4.92 for tetraplegia ng / mL). The serum total calcium was 9.54 ± 0.52 mg / dL, with no variation between individuals with paraplegia and tetraplegia. Mean levels of parathyroid hormone was 34.81 ± 10.84 pg / mL (33.43 ± 8.61 for paraplegia pg / ml and 39.59 ± 16.19 for tetraplegia pg / dL). Individuals with sun exposure more than 2 hours per day of vitamin D had higher values than those who were exposed to an hour per day (p = 0.001) and subjects with longer lesions showed lower values of vitamin D (p = 0.029). Conclusion : Vitamin D showed higher in subjects with a time of sun exposure greater than 2 hours per day and lowest in those with longer duration of spinal cord injury. The average value of vitamin D is in the range rated poor.